Pfizer's Approach to Validating Gait & Physical Activity Endpoints

Session details:

Although gait and physical activity measures captured via wearable sensors are among the most promising digital health technologies, questions remain around endpoint validation, regulatory acceptance, and the impact of ongoing algorithm updates. Hear how Pfizer is approaching validation of these endpoints while addressing strategies for maintaining scientific rigor as algorithms evolve.

• How does algorithm design and validation in healthy/different populations generalize across populations, scientifically and regarding regulatory interactions?

• How much “re-“validation is required for minor (i.e. bug fixes) to major (internal calculation methods) algorithm changes?